Cyclo-oxygenase-1 (COX-1) isoenzyme:
Correct Answer: Is predominant mode of action of Indomethacin
Description: Option A, C & E is incorrect as Cyclo-Oxygenase -1 (COX-1) is a constitutive Enzyme.
Option B is correct as – Indomethacin does affect it as it’s nonselective.
Option D is incorrect as COX-1, plays a central role in protection of the gastric mucosa, by helping in the synthesis of Prostaglandins.
Category:
Pharmacology
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