Progressive transformation of germinal centers (PTGC) is a precursor lesion of –
Correct Answer: Hodgkins lymphoma, lymphocytic predominant
Description: Lymphocytic predominance contains lymphocytic and histiocytic (L and H) variant. Thesse variants express B cell markers typical of germinal centre B cells. The IgH genes of L and H variant show evidence of ongoing somatic hypermutation,a modification that occurs only in germinal centre B cells. In 3%to5% of cases this type transforms in to a tumour resembling diffuse large B cell lymphoma. Reference; Robbins and Cotran Pathologic basis of disease.South Asia Edition volume 1.page no. 609,610
Category:
Pathology
Get More
Subject Mock Tests
Practice with over 200,000 questions from various medical subjects and improve your knowledge.
Attempt a mock test nowMock Exam
Take an exam with 100 random questions selected from all subjects to test your knowledge.
Coming SoonGet More
Subject Mock Tests
Try practicing mock tests with over 200,000 questions from various medical subjects.
Attempt a mock test now