Which of the following factors has maximum effect on filtration of a drug by the glomerulus ?

Correct Answer: Plasma protein binding
Description: - Main Factors determining glomerular filtration    Renal blood flow    Plasma protein binding - Lipid solubility does not affect glomerular filtration. - Ionization determines tubular reabsorption.  - Tubular secretion happens after glomerular filtration and so does not affect the process.
Category: Pharmacology
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