Regarding Candida true are –
Correct Answer: Commensal in skin
Description: Candidiasis (thrush) Superficial candidiasis is caused by Candida spp., mainly C. albicans. Manifestations include oropharyngeal and vaginal candidiasis ('thrush'), interigo and chronic paronychia. Superficial candidiasis often follows antibiotic therapy. Interigo is characterised by inflammation in skin folds with surrounding'satellite lesions'. Chronic paronychia is associated with frequent wetting of the hands. Superficial candidiasis is treated mainly with topical azoles , oral azoles being reserved for refractory or recurrent disease. Severe oropharyngeal and oesophageal candidiasis is a consequence of CD4+ T-lymphocyte depletion/ dysfunction, as in HIV infection . Recurrent vaginal or penile candidiasis may be a manifestation of diabetes mellitus. Rarely, mutations in the autoimmune regulator gene (AIRE) or signal transducer and activator of transcription 1 (STAT1) cause a syndrome of chronic mucocutaneous candidiasis . This is characterised by Candida infections of skin, mucosa and nails, with hyperkeratotic nails and erythematous periungual skin. Patients have cell-mediated immune defects against Candida and may have polyendocrinopathy and autoimmune features. Ref Harrison20th edition pg 1127
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