Which of the following drug is a SERM useful for treatment of osteoporosis?
Correct Answer: Raloxifene
Description: Ans. (A) Raloxifene(Ref: Katzung, 11/e p759; Goodman and Gilman, 11/e p1557; KDT 8/e p339)Raloxifene is a selective estrogen receptor modulator with estrogen agonistic action on bone and antagonistic action on breast and endometrium. It is therefore the preferred drug for the treatment and prevention of post-menopausal osteoporosis. Major adverse effect of this agent is increased risk of thromboembolism.
Category:
Pharmacology
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