Prognosis of melanoma depends ona) Stageb) Depth of melanoma of biopsyc) Duration of growthd) Site
Correct Answer: abd
Description: Prognosis of melanoma depends most importantly on staging. The most current staging system (of AJCC) takes into account following factors
depth of invasion (Breslow's thickness) - this is the single most important prognostic factor
ulceration - presence of ulceration carries worse prognosis.
lymph node status
satellite lession
distant metastasis
Other prognostic factor (not included in staging)
Site or anatomic location - people with lesion of the extermities have a better prognosis than people with melanomas of the head & neck or trunk. (feet and mucous membrane also have poor prognosis- Harrison)
Gender -females have better prognosis than males
Histologic type - Lentigo maligna has best prosnosis & acral lentiginous worst.
Old age especially > 60 have poorer prognosis.
Also know
The factor that most closely correlates with local recurrence is primary tumor ulceration (Sabiston 18/e p774)
Category:
Surgery
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