In thin basement membrane disease, the defect is in

Correct Answer: a3 and a4 chains of type IV collagen
Description: TBM disease (also known as benign familial hematuria and thin basement membrane nephropathy) is, along with IgA nephropathy, the most common cause of blood in the urine without any other symptoms. The only abnormal finding in this diseaseis a thinning of the basement membrane of the glomeruli (filters) in the kidneys. Refer robbins 9/e
Category: Pathology
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