The rationale for sucralfate therapy in peptic ulcers does not include :
Correct Answer: It has an acid neutralizing action.
Description: A Sucralfate binds to the base of the ulcer crater and inhibits the pepsin mediated protein hydrolysis. It by itself has no acid neutra-lizing action. Other mechanisms proposed for its effect are stimulation of prostaglandin synthesis and stimulation of local epider-mal growth factor.
Category:
Pharmacology
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