True about fresh frozen plasma -a) Used for treatment of antithrombin-3 deficiencyb) Used for treatment of Vit-K deficiencyc) Used for replacing factor VIII & IX, if deficiencyd) Best alternative for platelet
Correct Answer: ab
Description: Fresh frozen plasma (FFP)
FFP is defined as the fluid portion of human blood that has been centrifuged, separated, and frozen solid at -18°c within 6 hours.
FFP contains stable coagulation factors and plasma proteins : -
i. Fibrinogen
ii. Antithrombin
iii. Albumin & Immunoglobulin
iv. Protein C,S
v. Factor II, V, VII, ix, X, XI
Uses
There are few specific indications for the the use of FFP.
These indications are generally limited to the treatment of deficiency of coagulation proteins for which specific factor concentrates are unavailable or undesirable.
Indications for the use of FFP are : -
Deficiencies of factor II, V, VII, IX, X and XI when specific component therapy is neither available nor appropriate.
Emergency reversal of warfarin effect.
In vit K deficiency as replacement for Vit K dependent factors (II, VII, IX, X)
Antithrombin III deficiency
After massive blood transfusion.
In immunodeficiency as a source of immunoglobulin
TTP
Note : Options 'c' is partially correct, PPP can be used for deficiency of factor IX but not for factor VIII.
Category:
Pathology
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