Following is Hib conjugate vaccine –
Correct Answer: PRP with carrier
Description: Ans. is 'd > c' i.e., PRP with carrier > Capsular polysaccheride with carrier o Conjugated Hib vaccine include PRP (polyribosyl ribitol phasphate) covalently linked to carrier protein. PRP is the Capsular polysaccaride of H influenzae type B (Hib).o Currently three types of Hib (H influenzae type B) vaccines are available. These vary in -a) Protein carrier usedb) The molecular size of saccharidec) Mehtod of conjugation of protein to saccharide o These vaccines are -i) HbOC (mutant diphtheria toxin as the carrier protein)ii) PRP-T (Tetanus toxoid as the carrier protein)iii) PRP-OMP (major OMP of N meningitidis serogroup B as carrier)
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