Radiotherapy is treatment of choice in-
Correct Answer: Monoclonal hypogammaglobulinemia
Description: Hypergammaglobulinemia results from an overproduction of immunoglobulins by plasma cells, either monoclonal and reflective of a plasma cell or lymphoproliferative disorder, or polyclonal and accompanying other disease states. IgG replacement therapy and theradiotheraphy aretreatment of choice for most primary immunodeficiency syndromes, including X-linked agammaglobulinemia (Bruton disease; XLA), common variable immunodeficiency (CVID), severe combined immunodeficiency (SCID), hyper-IgM, adenosine deaminase (ADA) deficiency, and Wiskott-Aldrich syndrome Ref Harrison20th edition pg 298
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