A 52 year old male presented with features of purpura, ahralgia, neuropathy and glomerulonephritis. Low hemoglobin and high ESR was noticed in blood routine examination with mild alteration in the LFT with mild transaminase elevation. He has h/o blood transfusion in 1987 following an accident, at district hospital. What will be underlying pathology in this clinical setting?
Correct Answer: Essential mixed cryoglobulinemia
Description: Palpable purpura, ahralgia, neuropathy and glomerulonephritis are features of essential mixed cryoglobulinemia (EMC). Most cases of EMC are associated with chronic HCV infection. Chronic HCV infection produces asymptomatic transaminase elevation. Proper screening tests for HCV was not available in 1987 and blood transfusion in that period is a risk factor for HCV infection. Ref: Harrisons Principles of Internal Medicine, 18th Edition, Page 2798
Category:
Medicine
Get More
Subject Mock Tests
Practice with over 200,000 questions from various medical subjects and improve your knowledge.
Attempt a mock test nowMock Exam
Take an exam with 100 random questions selected from all subjects to test your knowledge.
Coming SoonGet More
Subject Mock Tests
Try practicing mock tests with over 200,000 questions from various medical subjects.
Attempt a mock test now