Transient acute adrenal insufficiency is seen with which of the following drug.
Correct Answer: Etomidate
Description: Etomidate causes adrenal gland suppression. It inhibits an enzyme 11 beta hydroxylase on essential enzyme for coisol synthesis. Etomidate has the highest incidence (40%) of post operative nausea and vomiting (PONV) among the intravenous anesthetics. Propofol has antiemetic propeies thereby reducing PONV. Other potential adverse effects of etomidate: Adrenocoical suppression Myoclonus Seizure precipitation Pain on injection
Category:
Anaesthesia
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