All the following conditions cause thrombocytopenia except –
Correct Answer: Iron deficiency anemia
Description: CAUSES OF THROMBOCYTOPENIA
DECREASED PRODUCTION OF PLATELETS
Selective impairment of platelet production
Drug-induced: alcohol, thiazides, cytotoxic drugs
Infections: measles, human immunodeficiency virus (HIV)
Nutritional deficiencies
B12, folate deficiency (megaloblastic anemia)
Bone marrow failure
Aplastic anemia
Bone marrow replacement
Leukaemia, disseminated cancer, granulomatous disease
Ineffective hematopoiesis
Myelodysplastic Syndromes
DECREASED PLATELET SURVIVAL
Immunologic destruction
Primary autoimmune
Chronic immune thrombocytopenic purpura
Acute immune thrombocytopenic purpura
Secondary autoimmune
SLE, B cell lymphoid neoplasms
Alloimmune : post-transfusion and neonatal
Drug-associated: quinidine, heparin, sulfa compounds
Infections: HIV, infectious mononucleosis (transient, mild), dengue fever
Non-immunologic destruction
Disseminated intravascular coagulation
Thrombotic microangiopathies
Giant hemangiomas
SEQUESTRATION
Hypersplenism
DILUTION
Transfusion
Category:
Pathology
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