A pt. has a pituitary tumour and pheochromocytoma and a thyroid nodule. Which Ca is most likely to occur –
Correct Answer: Medullary Ca
Description: This pt. is suffering from MEN Syndrome.
MEN (Multiple endocrine neoplasias) or MEA (Multiple endocrine adenomatosis) syndromes are characterized by the familial occurrence of multiple endocrine neoplasms.
3 types of MEN Syndrome are recognized.
a) MEN I (or Wermer's Syndrome*) consists of -
Pituitary adenoma (or hyperplasia)*
Parathyroid adenoma (or hyperplasia)*
Pancreatic islet cell hyperplasia, adenoma or carcinoma
Other less common manifestations :
foregut carcinoids
pheochromocytoma
subcutaneous or visceral lipomas
b) MEN HA ( or Sipple syndrome)
Medullary carcinoma of thyroid (MCT)*
Pheochromocytoma*
Parathyroid adenoma (or hyperplasia)*
Hirschsprung disease*
Cutaneous lichen amyloidosis*
c) MEN H B
Medullary carcinoma of thyroid (MCT)*
Pheochromocytoma *
Marfanoid features*
Mucocutaneous and gastrointestinal neuromas*
Thus this pt. is suffering from MEN II A or II B syndrome (Pituitary tumor in this pt. is still confusing the question, but still; answer is definitely MCT).
Category:
Surgery
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