Which of the following agent increases blood levels of theophylline?
Correct Answer: Erythromycin
Description: Factors Affecting Clearance of Theophylline: Increased clearance: Enzyme induction (mainly CYP1A2) by co-administered drugs (e.g., rifampicin, barbiturates, ethanol) Smoking (tobacco, marijuana) CYP1A2 induction High-protein, low-carbohydrate diet Barbecued meat Childhood Decreased clearance: CYP inhibition (cimetidine, erythromycin, ciprofloxacin, allopurinol, fluvoxamine, zileuton, zafirlukast) Congestive hea failure Liver disease Pneumonia Viral infection and vaccination High-carbohydrate diet Old age
Category:
Pharmacology
Get More
Subject Mock Tests
Practice with over 200,000 questions from various medical subjects and improve your knowledge.
Attempt a mock test nowMock Exam
Take an exam with 100 random questions selected from all subjects to test your knowledge.
Coming SoonGet More
Subject Mock Tests
Try practicing mock tests with over 200,000 questions from various medical subjects.
Attempt a mock test now