A lady presents with right knee swelling. Aspiration was done in which CPPD crystals were obtained. Next best investigation is –

Correct Answer: TSH
Description: Finding CPPD crystal in aspirated synovial fluid is diagnostic of CPPD arthropathy. CPPD arthropathy in some patients may be associated with :- Primary hyperparathyroidism, Hypothyroidism, Hemochromatosis, Hypomagnesemia, Hypophosphatasia. ANA (antinuclear antibody) is for SLE, RF (rheumatoid factor) is for rheumatoid arthritis and CPK (creatinine phosphokinase) is raised in dermatomyositis & polymyositis. So, among the given option only TSH is the relevant investigation in context of CPPD arthropathy as it may be associated with hypothyroidism.
Category: Orthopaedics
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