Complete wound strength in terms of collagen recovery is regained in what period of time?
Correct Answer: Never regained
Description: Net collagen accumulation peaks after 2-3 weeks after injury. Collagen production peaks after 6 weeks but is balanced by collagen degradation. Initial wound healing is notable for production of large amounts of randomly oriented collagen. During remodelling, this collagen becomes cross-linked and replaced with more organized collagen that is better arranged to resist mechanical stress. However, the final strength of new collagen never reaches the strength of uninjured collagen.
Category:
Pathology
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