A 40 year old woman is on treatment for CLL. Over the past few months she noticed swellings in the neck and axilla which was rapidly increasing in size. She complains of feeling feverish and experiences weight loss. Which of the following is responsible?
Correct Answer: Richter transformation
Description: CLL: Chronic Lymphocytic leukemia (CLL):- Neoplastic proliferation of native B cell; . Transformation to diffuse large B cell Lymphoma is marked by enlarging lymph node or spleen and worsening of symptom. This phenomenon is called Ritcher Transformation. Dx by flow cytometry positive for CD19/20, CD 5/23 Tx: Fludarabine is Drug of choice for management.
Category:
Pathology
Get More
Subject Mock Tests
Practice with over 200,000 questions from various medical subjects and improve your knowledge.
Attempt a mock test nowMock Exam
Take an exam with 100 random questions selected from all subjects to test your knowledge.
Coming SoonGet More
Subject Mock Tests
Try practicing mock tests with over 200,000 questions from various medical subjects.
Attempt a mock test now