Flipped pattern of LDH seen in:
Correct Answer: Acute Myocardial infarction
Description: Ref: hup://onlinelibrary, wiley.com/doi/10.1002/clc.4960091202/pdf http://health. nytimes.com/health/guides/test/ldh-isoenzytnes/overview.htmlExplanation:Serum lactate dehydrogenase (LDH) isoenzymesA possible explanation for the Hipped LDH pattern in the AMI patients (indicating some myocardial damage) could be myocytolysis and coagulation necrosis found on postmortem examinations.The conclusion of our study is that LDH isoenzymes should be measured in patients with AC I to determine the LDH 1.2 ratio.The finding of Ii "flipped" LDH pattern demonstrating myocardial damage, lacking in stable angina, may also be helpful in patients who developed the clinical picture of ACI more than 24 hours before arrival at the hospital, since by that rime the creatine kinase-MB may have already returned to normal.An additional advantage of measuring LDH isoenzymes in these patients may be that patients with "flipped" LDH pattern may need a longer rest and earlier coronary angiographic evaluation.
Category:
Pathology
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