Wich one of the following is the most common immunologic type of multiple myeloma?
Correct Answer: IgG, Kappa light chain
Description: On serum electrophoresis the paraprotein usually appears as a single narrow homogeneous M band component most commonly in the region of gamma globulin. Most frequent paraprotein is IgG seen in about 50% cases of myeloma, IgA in 25%and IgD in 1%. About 2/3 rd cases of myeloma excrete Bence Jones proteins in the urine, consisting of either kappa or lambda light chains , along with presence of Bence Jones paraproteins in the serum. Reference : Harsh Mohan textbook of pathology, 7th edition.Pg no.363
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