Drug of choice for the treatment of type 2 Brittle Asthma is?
Correct Answer: Subcutaneous epinephrine
Description: Type 2 Brittle asthma, are symptom-free patients developing sudden onset acute attack of asthma requiring mechanical ventilation or even death. These patients should ideally keep an auto-injector of epinephrine. Type 1 Brittle asthma is characterized by >40% variation in P.E.F.R for >50% of the time. It is managed with L.A.B.A + high dose inhaled coicosteroids and oral steroids. Long-term continuous subcutaneous infusion of P2 agonists like terbutaline is also given.
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