Termination is caused by all except
Correct Answer: Peptidyl transferase
Description: Termination Process of Translation After successive addition of amino acids , ribosome reaches the trerminator codon sequence (UAA ,UAG or UGA ) on the mRNA. Since , there is no tRNA bearing the corresponding anticodon sequence , the "A" site remains free. The release factor (RF) enters the site.The RF binds with rf3 NAD GTP. Theis complexalong hydrolyzes the peptide chain from the tRNA at the P site.This needs hydrolysis of GTP to GDP. The completed peptide chainis now released. Finally,80S ribosome dissociates into its component units of 60S and 40S. REF : DM VASUDEVAN TEXTBOOK , EIGHTH EDITION , Page no :583.
Category:
Biochemistry
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